Tuesday, October 2, 2012

Lipid Emulsion

Today I had the opportunity to sit and listen to an Aussie talk about lipid emulsion therapy.  But he did not just talk about what we know and review the literature.  Rather he talked about lipid emulsion therapy 2.0.  He presented his research into liposome therapy.  He is using phospolipids to sequester various agents.  Imagine a sphere with a hole in the middle.  The outside is the charged, phosphate layer.  The inner ring the lipid area.  The innermost core is an area whose pH can be manipulated.  By manipulating the core pH, the charge of the phosphate layer and the size of the lipid layer a variety of drugs are trapped.  In the future will we be seeing liposomes used to increase dosages of cancer chemotherapeutic agents?  Treat toxins that today we can only weep over?  If we do; you heard it here first. 

Along the lines of lipid emulsion therapy there are no less than eight abstracts at this toxicology meeting lauding its use.  There is a wide variety of toxins that were treated.  All very fascinating.

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